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FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels

Spinal astrocytes are coupled by connexin (Cx) gap junctions and express pannexin 1 (Px1) and purinergic receptors. Fibroblast growth factor 1 (FGF-1), which is released in spinal cord injury, activated spinal astrocytes in culture, induced secretion of ATP, and permeabilized them to relatively larg...

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Autors principals: Garré, Juan M., Retamal, Mauricio A., Cassina, Patricia, Barbeito, Luis, Bukauskas, Feliksas F., Sáez, Juan C., Bennett, Michael V. L., Abudara, Verónica
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012468/
https://ncbi.nlm.nih.gov/pubmed/21148774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013793107
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