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Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

The MIF2 gene of Saccharomyces cerevisiae has been implicated in mitosis. Here we provide genetic evidence that MIF2 encodes a centromere protein. Specifically, we found that mutations in MIF2 stabilize dicentric minichromosomes and confer high instability (i.e., a synthetic acentric phenotype) to c...

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Udgivet i:Mol Biol Cell
Principais autores: Meluh, P B, Koshland, D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301241/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7579695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.7.793
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