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Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin.

Cells selected for overexpression of the integrin alpha 5 beta 1 show decreased proliferation and loss of the transformed phenotype. We provide evidence that de novo expression of the integrin alpha 5 beta 1 in HT29 colon carcinoma cells results in the growth arrest of these cells as characterized b...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Varner, J A, Emerson, D A, Juliano, R L
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301232/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7579691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.6.725
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