A short segment within the cytoplasmic domain of the neural cell adhesion molecule (N-CAM) is essential for N-CAM-induced NF-κB activity in astrocytes

The neural cell adhesion molecule (N-CAM) is expressed on the surface of astrocytes, where its homophilic binding leads to the activation of the transcription factor NF-κB. Transfection of astrocytes with a construct encompassing the transmembrane region and the cytoplasmic domain of N-CAM (designat...

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Detalhes bibliográficos
Main Authors: Little, Edward B., Crossin, Kathryn L., Krushel, Leslie A., Edelman, Gerald M., Cunningham, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30122/
https://ncbi.nlm.nih.gov/pubmed/11226223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041597098
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