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Naloxone, but Not Valsartan, Preserves Responses to Hypoglycemia After Antecedent Hypoglycemia: Role of Metabolic Reprogramming in Counterregulatory Failure

OBJECTIVE: Hypoglycemia-associated autonomic failure (HAAF) constitutes one of the main clinical obstacles to optimum treatment of type 1 diabetes. Neurons in the ventromedial hypothalamus are thought to mediate counterregulatory responses to hypoglycemia. We have previously hypothesized that hypogl...

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Главные авторы: Poplawski, Michal M., Mastaitis, Jason W., Mobbs, Charles V.
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012195/
https://ncbi.nlm.nih.gov/pubmed/20811039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0326
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