OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects

OBJECTIVE: Metformin has been well characterized in vitro as a substrate of liver-expressed organic cation transporters (OCTs). We investigated the gene expression and protein levels of OCT-1 and OCT-2 in adipose tissue and during adipogenesis and evaluated their possible role in metformin action on...

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Detalhes bibliográficos
Main Authors: Moreno-Navarrete, José María, Ortega, Francisco J., Rodríguez-Hermosa, José-Ignacio, Sabater, Mònica, Pardo, Gerard, Ricart, Wifredo, Fernández-Real, José Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012168/
https://ncbi.nlm.nih.gov/pubmed/20956498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0805
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