Mutation or deletion of the Saccharomyces cerevisiae RAT3/NUP133 gene causes temperature-dependent nuclear accumulation of poly(A)+ RNA and constitutive clustering of nuclear pore complexes.

To identify genes whose products play potential roles in the nucleocytoplasmic export of messenger RNA, we isolated temperature-sensitive strains of Saccharomyces cerevisiae and examined them by fluorescent in situ hybridization. With the use of a digoxigen-tagged oligo-(dT)50 probe, we identified t...

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Hlavní autoři: Li, O, Heath, C V, Amberg, D C, Dockendorff, T C, Copeland, C S, Snyder, M, Cole, C N
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC301200/
https://ncbi.nlm.nih.gov/pubmed/7626806
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