In vivo expression of mammalian BiP ATPase mutants causes disruption of the endoplasmic reticulum.

BiP possesses ATP binding/hydrolysis activities that are thought to be essential for its ability to chaperone protein folding and assembly in the endoplasmic reticulum (ER). We have produced a series of point mutations in a hamster BiP clone that inhibit ATPase activity and have generated a species-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hendershot, L M, Wei, J Y, Gaut, J R, Lawson, B, Freiden, P J, Murti, K G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1995
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC301188/
https://ncbi.nlm.nih.gov/pubmed/7612964
Tagiau: Ychwanegu Tag
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