IKAP/hELP1 downregulation in neuroblastoma cells causes enhanced cell adhesion mediated by contactin overexpression

A splicing mutation in the IKBKAP gene encoding the IKAP/hELP1 (IKAP) protein was found to be the major cause of Familial Dysautonomia (FD). This mutation affects both the normal development and survival of sensory and sympathetic neurons of the peripheral nervous system (PNS). To understand the FD...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Cohen-Kupiec, Rachel, Weinstein, Shiri, Kantor, Gal, Peer, Dan, Weil, Miguel
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2010
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011265/
https://ncbi.nlm.nih.gov/pubmed/20671422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.4.4.12923
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