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Have we overestimated the benefit of human(ized) antibodies?
The infusion of animal-derived antibodies has been known for some time to trigger the generation of antibodies directed at the foreign protein as well as adverse events including cytokine release syndrome. These immunological phenomena drove the development of humanized and fully human monoclonal an...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3011222/ https://ncbi.nlm.nih.gov/pubmed/20935511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.6.13601 |
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