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Application of Modeling to Scale-up Dissolution in Pharmaceutical Manufacturing

Liquid mixing scale-up in pharmaceutical industry has often been based on empirical approach in spite of tremendous understanding of liquid mixing scale-up in engineering fields. In this work, we attempt to provide a model-based approach to scale-up dissolution process from a 2 l lab-scale vessel to...

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Detalhes bibliográficos
Main Authors: Koganti, Venkat, Carroll, Fred, Ferraina, Richard, Falk, Rick, Waghmare, Yogesh, Berry, Mark, Liu, Yang, Norris, Kenneth, Leasure, Robert, Gaudio, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011079/
https://ncbi.nlm.nih.gov/pubmed/20981586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9533-6
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