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Improved Albendazole Dissolution Rate in Pluronic 188 Solid Dispersions

Solids dispersions (SDs) have been proposed as an alternative to improve the dissolution rate of low solubility drugs. SDs containing albendazole (ABZ; 5, 10, 25, and 50% w/w) and Pluronic 188 (P 188) as hydrophilic carrier were formulated. The obtained SDs were assessed in comparison to physical mi...

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Hlavní autoři: Castro, Silvina G., Bruni, Sergio Sanchez, Lanusse, Carlos E., Allemandi, Daniel A., Palma, Santiago D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011078/
https://ncbi.nlm.nih.gov/pubmed/20945166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9517-6
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