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Preparation and Characterization of a Novel Co-processed Excipient of Chitin and Crystalline Mannitol

A co-processed excipient was prepared from commercially available crystalline mannitol and α-chitin using direct compression as well as spray, wet, and dry granulation. The effect of the ratio of the two components, percentage of lubricant and particle size, on the properties of the prepared co-proc...

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Autors principals: Daraghmeh, Nidal, Rashid, Iyad, Al Omari, Mahmoud M. H., Leharne, Stephen A., Chowdhry, Babur Z., Badwan, Adnan
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011072/
https://ncbi.nlm.nih.gov/pubmed/21052880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9523-8
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