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Evaluation of Mucoadhesive Hydrogels Loaded with Diclofenac Sodium–Chitosan Microspheres for Rectal Administration

Considering the advantageous for the rectal administration of non-steroidal anti-inflammatory drugs, the objective of this study was to formulate and evaluate rectal mucoadhesive hydrogels loaded with diclofenac-sodium chitosan (DFS-CS) microspheres. Hydroxypropyl methylcellulose (HPMC; 5%, 6%, and...

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Detalhes bibliográficos
Main Authors: El-Leithy, Eman S., Shaker, Dalia S., Ghorab, Mohamed K., Abdel-Rashid, Rania S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011065/
https://ncbi.nlm.nih.gov/pubmed/21108027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9544-3
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