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Mitochondrial Dysfunction and Apoptosis in Cumulus Cells of Type I Diabetic Mice

Impaired oocyte quality has been demonstrated in diabetic mice; however, the potential pathways by which maternal diabetes exerts its effects on the oocyte are poorly understood. Cumulus cells are in direct contact with the oocyte via gap junctions and provide essential nutrients to support oocyte d...

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Detalhes bibliográficos
Main Authors: Wang, Qiang, Frolova, Antonina I., Purcell, Scott, Adastra, Katie, Schoeller, Erica, Chi, Maggie M., Schedl, Tim, Moley, Kelle H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011018/
https://ncbi.nlm.nih.gov/pubmed/21209947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015901
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