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Mutation of proline-1003 to glycine in the epidermal growth factor (EGF) receptor enhances responsiveness to EGF.

We have shown previously that the epidermal growth factor (EGF) receptor is phosphorylated at Ser-1002 and that this phosphorylation is associated with desensitization of the EGF receptor. Ser-1002 is followed immediately by Pro-1003, a residue that may promote the adoption of a specific conformatio...

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Publicat a:Mol Biol Cell
Autors principals: Schuh, S M, Newberry, E P, Dalton, M A, Pike, L J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7812043/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.7.739
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