Effects of Thyrotropin-Releasing Hormone (TRH) on the Actions of Pentobarbital and Other Centrally Acting Drugs

Thyrotropin-releasing hormone (TRH) was found to antagonize pentobarbital-induced sleeping time and hypothermia. While 3 to 100 mg/kg of TRH reduced pentobarbital sleeping time when administered prior to the barbiturate, a dose-response relationship to TRH could not be established. However, doses of...

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Main Authors: Breese, George R., Cott, Jerry M., Cooper, Barrett R., Prange, Arthur J., Lipton, Morris A., Plotnikoff, Nicholas P.
Format: Artigo
Sprog:Inglês
Udgivet: 1975
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010748/
https://ncbi.nlm.nih.gov/pubmed/805836
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