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Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors

Malignant glioma is the most common brain tumor in adults and is associated with a very poor prognosis. Mutations in the p53 tumor suppressor gene are frequently detected in gliomas. p53 is well-known for its ability to induce cell cycle arrest, apoptosis, senescence, or differentiation following ce...

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Hlavní autoři: Hede, Sanna-Maria, Nazarenko, Inga, Nistér, Monica, Lindström, Mikael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010739/
https://ncbi.nlm.nih.gov/pubmed/21209724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/852970
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