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Inflammation, HIF-1, and the Epigenetics That Follows
We summarize recent findings linking inflammatory hypoxia to chromatin modifications, in particular to repressive histone signatures. We focus on the role of Hypoxia-Induced Factor-1 in promoting the activity of specific histone demethylases thus deeply modifying chromatin configuration. The consequ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010677/ https://ncbi.nlm.nih.gov/pubmed/21197398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/263914 |
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