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Human gene targeting by viral vectors
Stable transduction of mammalian cells typically involves random integration of viral vectors by non-homologous recombination. Here we report that vectors based on adeno-associated virus (AAV) can efficiently modify homologous human chromosomal target sequences. Both integrated neomycin phosphotrans...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010411/ https://ncbi.nlm.nih.gov/pubmed/9537413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng0498-325 |
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