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Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae.

Expression of pp60v-src, the transforming protein of Rous sarcoma virus, arrests the growth of the yeast Saccharomyces cerevisiae. To determine the basis of this growth arrest, yeast strains were constructed that expressed either wild-type v-src or various mutant v-src genes under the control of the...

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Pubblicato in:Mol Biol Cell
Autori principali: Florio, M, Wilson, L K, Trager, J B, Thorner, J, Martin, G S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301037/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8049521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.3.283
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