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Potent Ligands for Prokaryotic UDP-Galactopyranose Mutase That Exploit an Enzyme Subsite

[Image: see text] UDP-Galactopyranose mutase (UGM or Glf), which catalyzes the interconversion of UDP-galactopyranose and UDP-galactofuranose, is implicated in the viability and virulence of multiple pathogenic microorganisms. Here we report the synthesis of high-affinity ligands for UGM homologs fr...

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Autori principali: Dykhuizen, Emily C., Kiessling, Laura L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010353/
https://ncbi.nlm.nih.gov/pubmed/19067595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802094p
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