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Advanced Glycation Endproducts on Stored Erythrocytes increase Endothelial Reactive Oxygen Species Generation through Interaction with RAGE

BACKGROUND: Recent evidence suggests that storage induced alterations of the red blood cell (RBC) are associated with adverse consequences in susceptible hosts. As RBCs have been shown to form Advanced Glycation Endproducts (AGEs) following increased oxidative stress and under pathologic conditions,...

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Detalhes bibliográficos
Main Authors: Mangalmurti, Nilam S, Chatterjee, Shampa, Cheng, Guanjun, Andersen, Emily, Mohammed, Aishat, Siegel, Donald L, Schmidt, Ann Marie, Albelda, Steven M, Lee, Janet S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010325/
https://ncbi.nlm.nih.gov/pubmed/20492604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2010.02689.x
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