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Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β
While both 17β-estradiol (E2) and progesterone (P4) are neuroprotective in several experimental paradigms, P4 also counteracts E2 neuroprotective effects. We recently reported that a 4 h treatment of cultured hippocampal slices with P4 following a prolonged (20 h) treatment with E2 eliminated estrog...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010223/ https://ncbi.nlm.nih.gov/pubmed/20977477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07038.x |
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