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Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50

Both connexin 50 (Cx50) and aquaporin 0 (AQP0) have important roles in lens development and homeostasis, and their mutations are associated with human congenital cataracts. We have previously shown that Cx50 directly interacts with AQP0. Here, we demonstrate the importance of the Cx50 intracellular...

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Detalhes bibliográficos
Main Authors: Liu, Jialu, Xu, Ji, Gu, Sumin, Nicholson, Bruce J., Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010190/
https://ncbi.nlm.nih.gov/pubmed/21172802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.072652
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