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Differential sensitivity of Ca(2+) wave and Ca(2+) spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes

Spontaneous Ca(2+) waves in cardiac muscle cells are thought to arise from the sequential firing of local Ca(2+) sparks via a fire–diffuse–fire mechanism. This study compares the ability of the ryanodine receptor (RyR) blocker ruthenium red (RuR) to inhibit these two types of Ca(2+) release in perme...

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Autores principales: MacQuaide, N, Ramay, H R, Sobie, E A, Smith, G L
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010142/
https://ncbi.nlm.nih.gov/pubmed/20921197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.193375
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