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Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast

Which transcription factors control the distribution of metabolic fluxes under a given condition? We address this question by systematically quantifying metabolic fluxes in 119 transcription factor deletion mutants of Saccharomyces cerevisiae under five growth conditions. While most knockouts did no...

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Detalhes bibliográficos
Main Authors: Fendt, Sarah-Maria, Oliveira, Ana Paula, Christen, Stefan, Picotti, Paola, Dechant, Reinhard Christoph, Sauer, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010106/
https://ncbi.nlm.nih.gov/pubmed/21119627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.91
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