Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1(*/* )mice with collagen-induced chronic arthritis

BACKGROUND: Collagen-induced arthritis (CIA) is an often-used murine model for human rheumatoid arthritis (RA). Earlier studies have shown potent anti-arthritic effects with the female sex hormone estradiol and the selective estrogen receptor modulator (SERM) raloxifene in CIA in DBA/1-mice. B10.Q-n...

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Main Authors: Jochems, Caroline, Islander, Ulrika, Erlandsson, Malin, Engdahl, Cecilia, Lagerquist, Marie, Gjertsson, Inger, Ohlsson, Claes, Holmdahl, Rikard, Carlsten, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009959/
https://ncbi.nlm.nih.gov/pubmed/21159208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-11-284
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