Intrarenal Renin Angiotensin System Revisited: ROLE OF MEGALIN-DEPENDENT ENDOCYTOSIS ALONG THE PROXIMAL NEPHRON

The existence of a local renin angiotensin system (RAS) of the kidney has been established. Angiotensinogen (AGT), renin, angiotensin-converting enzyme (ACE), angiotensin receptors, and high concentrations of luminal angiotensin II have been found in the proximal tubule. Although functional data hav...

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Detalhes bibliográficos
Main Authors: Pohl, Marcus, Kaminski, Henriette, Castrop, Hayo, Bader, Michael, Himmerkus, Nina, Bleich, Markus, Bachmann, Sebastian, Theilig, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009920/
https://ncbi.nlm.nih.gov/pubmed/20966072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.150284
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