VGLUT2 expression in primary afferent neurons is essential for normal acute pain and injury-induced heat hypersensitivity

Dorsal root ganglia (DRG) neurons, including the nociceptors that detect painful thermal, mechanical, and chemical stimuli, transmit information to spinal cord neurons via glutamatergic and peptidergic neurotransmitters. However, the specific contribution of glutamate to pain generated by distinct s...

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Detalhes bibliográficos
Main Authors: Scherrer, Grégory, Low, Sarah A., Wang, Xidao, Zhang, Jie, Yamanaka, Hiroki, Urban, Rochelle, Solorzano, Carlos, Harper, Blaine, Hnasko, Thomas S., Edwards, Robert H., Basbaum, Allan I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009833/
https://ncbi.nlm.nih.gov/pubmed/21135246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013413108
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