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Design of small molecules that target metal-Aβ species and regulate metal-induced Aβ aggregation and neurotoxicity
The accumulation of metal ions and amyloid-β (Aβ) aggregates found in the brain of patients with Alzheimer’s disease (AD) has been suggested to be involved in AD pathogenesis. To investigate metal-Aβ-associated pathways in AD, development of chemical tools to target metal-Aβ species is desired. Only...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009803/ https://ncbi.nlm.nih.gov/pubmed/21131570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006091107 |
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