Hypoxia Induces an Immunodominant Target of Tuberculosis Specific T Cells Absent from Common BCG Vaccines

M. tuberculosis (MTB) species-specific antigenic determinants of the human T cell response are important for immunodiagnosis and vaccination. As hypoxia is a stimulus in chronic tuberculosis infection, we analyzed transcriptional profiles of MTB subject to 168 hours of hypoxia to test the hypothesis...

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Detaylı Bibliyografya
Asıl Yazarlar: Gideon, Hannah Priyadarshini, Wilkinson, Katalin Andrea, Rustad, Tige R., Oni, Tolu, Guio, Heinner, Kozak, Robert Andrew, Sherman, David R., Meintjes, Graeme, Behr, Marcel A., Vordermeier, Hans Martin, Young, Douglas Brownlee, Wilkinson, Robert John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009603/
https://ncbi.nlm.nih.gov/pubmed/21203487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001237
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