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Disruption of endoplasmic reticulum to Golgi transport leads to the accumulation of large aggregates containing beta-COP in pancreatic acinar cells.

When transport between the rough endoplasmic reticulum (ER) and Golgi complex is blocked by Brefeldin A (BFA) treatment or ATP depletion, the Golgi apparatus and associated transport vesicles undergo a dramatic reorganization. Because recent studies suggest that coat proteins such as beta-COP play a...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Hendricks, L C, McCaffery, M, Palade, G E, Farquhar, M G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8507897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.4.413
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