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Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: New insights on structure and function relationship

Nicotinamide mononucleotide adenylyltransferase (NMNAT) catalyzes the formation of NAD by means of nucleophilic attack by 5′-phosphoryl of NMN on the α-phosphoryl group of ATP. Humans possess three NMNAT isozymes (NMNAT1, NMNAT2, and NMNAT3) that differ in size and sequence, gene expression pattern,...

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Detalhes bibliográficos
Main Authors: Brunetti, Lucia, Di Stefano, Michele, Ruggieri, Silverio, Cimadamore, Flavio, Magni, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009411/
https://ncbi.nlm.nih.gov/pubmed/20954240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.526
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