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Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading.

Release of arachidonic acid (AA) and subsequent formation of a lipoxygenase (LOX) metabolite(s) is an obligatory signal to induce spreading of HeLa cells on a gelatin substratum (Chun and Jacobson, 1992). This study characterizes signaling pathways that follow the LOX metabolite(s) formation. Levels...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Chun, J S, Jacobson, B S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Cell Biology 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8485318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.3.271
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