Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factors.

Two widely used hepatoma cell lines, mouse BW1J and human HepG2, express gene products characteristic of fetal hepatocytes, including serum albumin, whereas reporter genes driven by the albumin promoter are expressed at very low levels compared with highly differentiated hepatoma cells. We have inve...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Rollier, A, DiPersio, C M, Cereghini, S, Stevens, K, Tronche, F, Zaret, K, Weiss, M C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8443410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.1.59
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