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Biological impact of missing-value imputation on downstream analyses of gene expression profiles

Motivation: Microarray experiments frequently produce multiple missing values (MVs) due to flaws such as dust, scratches, insufficient resolution or hybridization errors on the chips. Unfortunately, many downstream algorithms require a complete data matrix. The motivation of this work is to determin...

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Détails bibliographiques
Auteurs principaux: Oh, Sunghee, Kang, Dongwan D., Brock, Guy N., Tseng, George C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008641/
https://ncbi.nlm.nih.gov/pubmed/21045072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq613
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