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Fused-core silica column ultra performance liquid chromatography – ion trap tandem mass spectrometry for determination of global DNA methylation status

Epigenetic modifications, such as DNA methylation, play key roles in transcriptional regulation of gene expression. More recently, global DNA methylation levels have been documented to be altered in several diseases, including cancer, and as the result of exposure to environmental toxicants. Based o...

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Detalhes bibliográficos
Main Authors: Yang, Ill, Fortin, Marie C., Richardson, Jason R., Buckley, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008593/
https://ncbi.nlm.nih.gov/pubmed/20950581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.10.012
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