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Na(+)-dependent transporters mediate HCO(3)(–) salvage across the luminal membrane of the main pancreatic duct

To study the roles of Na(+)-dependent H(+) transporters, we characterized H(+) efflux mechanisms in the pancreatic duct in wild-type, NHE2(–/–), and NHE3(–/–) mice. The pancreatic duct expresses NHE1 in the basolateral membrane, and NHE2 and NHE3 in the luminal membrane, but does not contain NHE4 or...

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Autori principali: Lee, Min Goo, Ahn, Wooin, Choi, Joo Young, Luo, Xiang, Seo, Jeong Taeg, Schultheis, Patrick J., Shull, Gary E., Kim, Kyung Hwan, Muallem, Shmuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC300855/
https://ncbi.nlm.nih.gov/pubmed/10841524
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