Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

Abdominal aortic aneurysms represent a life-threatening condition characterized by chronic inflammation, destructive remodeling of the extracellular matrix, and increased local expression of matrix metalloproteinases (MMPs). Both 92-kD gelatinase (MMP-9) and macrophage elastase (MMP-12) have been im...

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Bibliografiset tiedot
Päätekijät: Pyo, Robert, Lee, Jason K., Shipley, J. Michael, Curci, John A., Mao, Dongli, Ziporin, Scott J., Ennis, Terri L., Shapiro, Steven D., Senior, Robert M., Thompson, Robert W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2000
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC300851/
https://ncbi.nlm.nih.gov/pubmed/10841523
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