Statins Enhance Formation of Phagocyte Extracellular Traps

Statins are inhibitors of 3-hydroxy 3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in cholesterol biosynthesis. Several recent clinico-epidemiologic studies have revealed that patients receiving statin therapy have reduced mortality associated with severe bacterial infecti...

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Hauptverfasser: Chow, Ohn A., von Köckritz-Blickwede, Maren, Bright, A. Taylor, Hensler, Mary E., Zinkernagel, Annelies S., Cogen, Anna L., Gallo, Richard L., Monestier, Marc, Wang, Yanming, Glass, Christopher K., Nizet, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008410/
https://ncbi.nlm.nih.gov/pubmed/21075355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.10.005
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