Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule

The proximal convoluted tubule (PCT) reabsorbs most of the filtered bicarbonate. Proton secretion is believed to be mediated predominantly by an apical membrane Na(+)/H(+) exchanger (NHE). Several NHE isoforms have been cloned, but only NHE3 and NHE2 are known to be present on the apical membrane of...

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Pubblicato in:	J Clin Invest
Autori principali:	Choi, Joo Young, Shah, Mehul, Lee, Min Goo, Schultheis, Patrick J., Shull, Gary E., Muallem, Shmuel, Baum, Michel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10772659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9260
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