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Nitrite in saliva increases gastric mucosal blood flow and mucus thickness

Salivary nitrate from dietary or endogenous sources is reduced to nitrite by oral bacteria. In the acidic stomach, nitrite is further reduced to NO and related compounds, which have potential biological activity. We used an in vivo rat model as a bioassay to test effects of human saliva on gastric m...

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Detalhes bibliográficos
Main Authors: Björne, Håkan, Petersson, Joel, Phillipson, Mia, Weitzberg, Eddie, Holm, Lena, Lundberg, Jon O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300767/
https://ncbi.nlm.nih.gov/pubmed/14702114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419019
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