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Nitrite in saliva increases gastric mucosal blood flow and mucus thickness

Salivary nitrate from dietary or endogenous sources is reduced to nitrite by oral bacteria. In the acidic stomach, nitrite is further reduced to NO and related compounds, which have potential biological activity. We used an in vivo rat model as a bioassay to test effects of human saliva on gastric m...

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Bibliographic Details
Main Authors: Björne, Håkan, Petersson, Joel, Phillipson, Mia, Weitzberg, Eddie, Holm, Lena, Lundberg, Jon O.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC300767/
https://ncbi.nlm.nih.gov/pubmed/14702114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419019
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