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Astrocytes in the Retrotrapezoid Nucleus Sense H(+) by Inhibition of a Kir4.1–Kir5.1-Like Current and May Contribute to Chemoreception by a Purinergic Mechanism

Central chemoreception is the mechanism by which CO(2)/pH sensors regulate breathing in response to tissue pH changes. There is compelling evidence that pH-sensitive neurons in the retrotrapezoid nucleus (RTN) are important chemoreceptors. Evidence also indicates that CO(2)/H(+)-evoked adenosine 5′-...

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Autors principals: Wenker, Ian C., Kréneisz, Orsolya, Nishiyama, Akiko, Mulkey, Daniel K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007661/
https://ncbi.nlm.nih.gov/pubmed/20926613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00544.2010
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