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Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice

Diabetic hyperglycemia increases ischemic brain damage in experimental animals and humans. The mechanisms are unclear but may involve enhanced apoptosis in penumbral regions. Estrogen is an established neuroprotectant in experimental stroke. Our previous study demonstrated that female diabetic db/db...

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Detalhes bibliográficos
Main Authors: Zhang, Liqun, Nair, Aji, Krady, Kyle, Corpe, Christopher, Bonneau, Robert H., Simpson, Ian A., Vannucci, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300764/
https://ncbi.nlm.nih.gov/pubmed/14702112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418336
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