Determination of Residual Epichlorohydrin in Sevelamer Hydrochloride by Static Headspace Gas Chromatography with Flame Ionization Detection

A sensitive static headspace gas chromatographic method was developed and validated for the determination of residual epichlorohydrin (ECH) in sevelamer hydrochloride (SVH) drug substance. This method utilized a Phenomenex Zebron ZB-WAX GC column, helium as carrier gas with flame ionization detectio...

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Autori principali: Karthikeyan, Kaliaperumal, Arularasu, Govindasamy T., Devaraj, Perumalsamy, Pillai, Karnam Chandrasekara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Österreichische Apotheker-Verlagsgesellschaft 2010
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007613/
https://ncbi.nlm.nih.gov/pubmed/21179319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1007-20
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