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Development and Validation of a Stability-Indicating RP-HPLC Method for Duloxetine Hydrochloride in its Bulk and Tablet Dosage Form

The objective of the present work was to develop a stability-indicating RP-HPLC method for duloxetine hydrochloride (DUL) in the presence of its degradation products generated from forced decomposition studies. The drug substance was found to be susceptible to stress conditions of acid hydrolysis. T...

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Autors principals: Chhalotiya, Usmangani K., Bhatt, Kashyap K., Shah, Dimal A., Baldania, Sunil L.
Format: Artigo
Idioma:Inglês
Publicat: Österreichische Apotheker-Verlagsgesellschaft 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007604/
https://ncbi.nlm.nih.gov/pubmed/21179321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1009-11
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