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Development and Validation of a Stability-Indicating RP-HPLC Method for Duloxetine Hydrochloride in its Bulk and Tablet Dosage Form

The objective of the present work was to develop a stability-indicating RP-HPLC method for duloxetine hydrochloride (DUL) in the presence of its degradation products generated from forced decomposition studies. The drug substance was found to be susceptible to stress conditions of acid hydrolysis. T...

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Bibliografiske detaljer
Main Authors: Chhalotiya, Usmangani K., Bhatt, Kashyap K., Shah, Dimal A., Baldania, Sunil L.
Format: Artigo
Sprog:Inglês
Udgivet: Österreichische Apotheker-Verlagsgesellschaft 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007604/
https://ncbi.nlm.nih.gov/pubmed/21179321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1009-11
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