Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level

We determined whether postnatal pulmonary hypertension induced by 70% of pregnancy at high altitude (HA) persists once the offspring return to sea level and investigated pulmonary vascular mechanisms operating under these circumstances. Pregnant ewes were divided into two groups: conception, pregnan...

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Main Authors: Herrera, Emilio A., Riquelme, Raquel A., Ebensperger, Germán, Reyes, Roberto V., Ulloa, César E., Cabello, Gertrudis, Krause, Bernardo J., Parer, Julian T., Giussani, Dino A., Llanos, Aníbal J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007194/
https://ncbi.nlm.nih.gov/pubmed/20881096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00123.2010
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