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Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice
NKT cells in the mouse recognize antigen in the context of the MHC class I–like molecule CD1d and play an important role in peripheral tolerance and protection against autoimmune and other diseases. NKT cells are usually activated by CD1d-presented lipid antigens. However, peptide recognition in the...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Clinical Investigation
2010
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3007151/ https://ncbi.nlm.nih.gov/pubmed/21157037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43964 |
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