Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

Human leukemic stem cells, like other cancer stem cells, are hypothesized to be rare, capable of incomplete differentiation, and restricted to a phenotype associated with early hematopoietic progenitors or stem cells. However, recent work in other types of tumors has challenged the cancer stem cell...

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Bibliographische Detailangaben
Hauptverfasser: Sarry, Jean-Emmanuel, Murphy, Kathleen, Perry, Robin, Sanchez, Patricia V., Secreto, Anthony, Keefer, Cathy, Swider, Cezary R., Strzelecki, Anne-Claire, Cavelier, Cindy, Récher, Christian, Mansat-De Mas, Véronique, Delabesse, Eric, Danet-Desnoyers, G., Carroll, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007135/
https://ncbi.nlm.nih.gov/pubmed/21157036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41495
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